3MT36: PHYTOCHEMICAL, ANTIOXIDANT, AND ANTIBACTERIAL ACTIVITIES FROM THE LEAF EXTRACTS OF Strobilanthes Crispus (L.)

Cassy Lugak Universiti Teknologi MARA (UiTM)

VIC24 | Virtual 3MT

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The leaves of Strobilanthes crispus (L.) have been traditionally utilised in Malaysia and Indonesia as a form of folk medicine, commonly prepared as a tea or used in cooking for its nutritional benefits. However, there is still limited information about this plant, which was only discovered in East Malaysia and one from Kuching, Sarawak. This research aims to identify selected phytochemicals present in the leaf of S. crispus. (L.). The leaves undergo a maceration extraction process using hexane, ethyl acetate, and methanol. The antioxidant activity is analysed using the DPPH free radical scavenging method, while antibacterial activity is tested using the disc diffusion method. The methanol crude extract from the leaves exhibits positive results for all tested compounds, including alkaloids, flavonoids, terpenoids, tannins, and phenols. However, the ethyl acetate crude extract shows positivity only for alkaloids, phenols, and flavonoids, and the hexane crude extract is positive only for alkaloids and terpenoids. The methanol extract's antioxidant activity is 87.08% with an IC50 value of 126.50 ppm, while the ethyl acetate extract demonstrates 94.65% antioxidant activity with an IC50 value of 217.97 ppm. Unfortunately, the free radical scavenging activity of the hexane extract could not be determined compared to the standard ascorbic acid used. Regarding antibacterial activity, the S. crispus (L.) extract shows no activity against selected bacteria, as no zone of inhibition was observed. While S. crispus (L.) extract demonstrates potential in secondary metabolites and antioxidant activity, its antibacterial activity appears comparatively lower than the standard antibiotics used in this study.