Virtual Booth

Antibacterial resistance refers to the ability of bacteria to withstand the effects of antibiotics, rendering them ineffective in treating bacterial infections. Strobilanthes crispus L. contains several biologically active secondary metabolites that are responsible for its pharmaceutical quality. However, scientific research about this plant is still lacking. This study conducted the phytochemical screening to investigate the presence of several selected phytochemical groups. Furthermore, this study was continued by screening the active metabolites that can act as antioxidant and antibacterial agents by 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay and disc diffusion assay, respectively. Moreover, antioxidant activity was analyzed using an ultraviolet-visible spectrophotometer. For phytochemical screening, n-hexane and ethyl acetate extract only displayed the presence of the alkaloids group, meanwhile, methanol extract showed the presence for all tested phytochemicals which are flavonoids, terpenoids, phenols, alkaloids, and tannins. For antioxidants screening, methanol extract showed the highest percentage of inhibition, followed by ethyl acetate and n-hexane with 47.31%, 38.55%, and 11.59%, respectively. Thus, indicating no antioxidant properties due to the percentage inhibition of DPPH assays below 50%. For antibacterial screening, all extracts displayed inactive activities against all tested bacteria including two Gram-positive and four Gram-negative which are Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus, Shigella flexneri, Enterobacter aerogenes, Salmonella typhimurium, and Escherichia coli, respectively. Hence, extracts from S. crispus L. collected in Duyong, Melaka showed no active secondary metabolites as antioxidant as well as antibacterial agents.