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Our study focuses on identifying and extracting chemical compounds from two medicinal plants, Elettariopsis curtisii and Brucea amarissima. Elettariopsis curtisii, also known as ‘pokok pepijat’ has the ability to dissolve bioactive compounds. Brucea amarissiima also called as ‘lada pahit’ contains anti-cancer compounds. Active compounds such as alkaloids and flavonoids were performed using Attenuated Total Reflectance-Fourier Transform Infrared (ATR-FTIR) spectroscopy. These compounds possesed potential health benefits such as cardioprotective and anti-inflammatory. In addition, we incorporated the saponification process to enhance our understanding of the chemical composition of these plants and supports future studies on their medicinal and hygienic applications.