ST7: Cellucide: Plant-Derived Mosquito Larvicide Stabilised By Cellulose Nanocrystals

Susana Wong Siew Tin Department Of Chemistry, Faculty Of Science And Mathematics, Universiti Pendidikan Sultan Idris.

Dengue fever remains a highly critical public health challenge in Malaysia, with 26,058 infection cases recorded within a brief 140-day period in 2026. To address the World Health Organization (WHO)’s urgent mandate for optimised larval source management, this study introduces Cellucide, an innovative plant-derived mosquito larvicide. This green formulation leverages potent, bioactive rose geranium essential oil encapsulated within sustainable cellulose nanocrystals acting as a stabilising carrier network. Cellucide was comprehensively characterised utilising FTIR and STEM techniques, confirming the successful integration of bioactive constituents within a highly stable, monodisperse nanocrystalline framework. Larvicidal efficacy trials evaluated against third-instar Aedes aegypti larvae demonstrated an exceptional mortality rate of 100.0 %. These promising findings reveal that Cellucide serves as a potent, eco-friendly vector control agent capable of mitigating widespread mosquito-borne diseases. Strategically, Cellucide aligns perfectly with the WHO’s Integrated Vector Management framework and Malaysia's National Green Technology Policy. By providing a sustainable alternative to synthetic chemical agents, this bio-based formulation directly advances United Nations Sustainable Development Goal 3 (Good Health and Well-Being). Ultimately, Cellucide delivers a highly scalable, non-toxic solution that bridges the needs of modern public healthcare with eco-friendly environmental management.